Proteins form the essential, insoluble backbone of our cellular environment. We genetically engineer protein-based materials to mimic those naturally found in this environment. By borrowing from nature’s toolbox, we further modify these proteins to assemble only with body heat allowing complex cellular environments to be created with simple solution injections. These materials can be handled as simple, low-viscosity fluids, easily adaptable to current state-of-the-art procedures.
Co-Injection with Fat
Because our materials only form a scaffold at body temperature, they can be easily seeded with cells or tissue such as fat acquired via liposuction. Our material provides a natural, shapable scaffold that mimics tissue structure, stabilizing the shape and increasing the effective volume of the injected fat.
To prepare for fat grafting, healthy fat is liposuctioned from a donor site.
Combine with Matrix
Rather than go directly to the reconstruction site, the liposuctioned fat is mixed with our Fractomer matrix.
This mixture of tissue and biomatrix is injected as a single slurry into the tissue reconstruction site.
Under the simple action of body heat, Fractomer rapidly switches from a liquid to a solid scaffold.
The Fractomer scaffold provides shape, structure, and nutrient flow to the grafted fat.
Current bio-compatible materials are inadequate for soft-tissue reconstruction as they are either costly, side-effect prone allografts or short-lived synthetic polymer placeholders. By genetically engineering artificial proteins that mimic natural cellular environments, we can merge the low-cost manufacturing and design control of synthetic polymers with the natural tissue integration of native proteins.